Thermal analysis comprises a group of techniques in which a physical property of a substance is measured to a controlled temperature program. One of the thermal analysis techniques, Differential Scanning Calorimetry is presented in this review. It is a highly sensitive technique to study the thermotropic properties of many different biological macromolecules and extracts. The results given from the Differential Scanning Calorimetry curves depend on the preparation of the sample, and on the instrument sensitivity. Several types of Differential Scanning Calorimetry instruments are described along with their applications.
Differential Scanning Calorimetry | Janna Maranas Research Group
Studies of lipid phase transitions in some model membranes using differential scanning calorimetry
The objective of this study was to prepare aripiprazole ARI -loaded solid dispersions SDs to enhance solubility and dissolution via hot-melt extrusion HME technology. ARI was chosen due to its poorly water-soluble properties. Solubility screenings of various polymers and acidifiers were performed to select appropriate excipients for the SD.